Anti-MYL9 Antibody

This polyclonal antibody from Antibodies.com targets MYL9 (myosin light chain 9), the regulatory light chain of non-muscle and smooth muscle myosin II. The unconjugated rabbit polyclonal reagent is supplied as a 100 µl volume and is validated for Western blot (WB) and immunohistochemistry (IHC) workflows against human, mouse, and rat samples. Researchers commonly apply anti-MYL9 antibodies to investigate smooth muscle contraction, cytoskeletal remodeling, cytokinesis, and cell migration, because phosphorylation of MYL9 at Ser19 by myosin light chain kinase (MLCK) is a central regulatory step in actomyosin contractility. The reagent is also useful in studies of megakaryocyte differentiation, platelet biogenesis, vascular smooth muscle physiology, and tumor cell invasion, where altered MYL9 expression or phosphorylation status has been reported in the literature. As a primary antibody, it supports detection of endogenous MYL9 protein in tissue sections and cell lysates, enabling cross-species comparative work between rodent disease models and human clinical specimens within a single experimental workflow.