Anti-MYL2 Antibody

Raised in rabbit against the cardiac sarcomeric regulatory subunit myosin light chain 2, this polyclonal reagent from Antibodies.com recognizes an epitope conserved across human, mouse, and rat orthologs. The 19 kDa target modulates actin-myosin cross-bridge kinetics during striated muscle contraction, and the unconjugated antibody is widely used to track ventricular specification in stem cell-derived cardiomyocytes, characterize sarcomere assembly by immunofluorescence, and probe remodeling in models of hypertrophic cardiomyopathy. Standard Western blot protocols on cardiac tissue lysates resolve a single band near the expected molecular weight, while the polyclonal format provides robust signal amplification on low-abundance samples. Each vial contains 100 µl of antibody, which users typically aliquot into working stocks to limit repeated freeze-thaw cycles and preserve long-term affinity.