Anti-MYL2 Antibody

This rabbit polyclonal IgG antibody recognizes myosin regulatory light chain 2 (MYL2), a roughly 19 kDa sarcomeric protein expressed in ventricular cardiomyocytes and slow-twitch skeletal muscle fibers. Produced in rabbit and supplied as an unconjugated reagent in a 200 µL format, the preparation is validated for Western blot and immunofluorescence workflows on human and mouse samples, supporting both chemiluminescent detection in cell and tissue lysates and high-resolution imaging of cardiac sections. MYL2 is a well-established marker of ventricular cardiomyocyte identity, commonly used to track cardiac differentiation of pluripotent stem cells, characterize engineered heart tissue, and probe sarcomere assembly in models of hypertrophic cardiomyopathy. The unconjugated format offers flexibility for downstream secondary antibody pairing, enabling custom fluorophore or enzyme choices in immunofluorescence staining and reproducible band detection across Western blot membranes. Researchers investigating cardiomyopathy, contractile regulation, and cardiac lineage specification routinely combine this ventricular marker with atrial markers such as MYL7 to distinguish chamber-specific cardiomyocyte populations. Each lot is shipped refrigerated to preserve IgG stability, and aliquoting upon arrival is recommended to limit freeze-thaw cycles and protect long-term reagent activity. Host species, clonality, isotype, reactivity profile, and target specificity are documented on the accompanying datasheet provided by Antibodies.com, giving users the technical detail needed to plan reproducible immunoassays in cardiomyocyte biology, developmental studies, and translational cardiac disease research.