Anti-MYH1 Antibody

Produced by Antibodies.com, this rabbit polyclonal reagent recognizes myosin heavy chain IIx (MyHC-IIx), the contractile protein encoded by the MYH1 gene and a defining marker of fast-twitch glycolytic (type IIX) skeletal muscle fibers. The antibody is supplied unconjugated at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, shipped as a 100 µl working aliquot. It is validated for Western blot, immunohistochemistry, and immunofluorescence applications, and it cross-reacts with mouse and rat orthologues alongside its human target, enabling comparative fiber-typing studies across rodent exercise, injury, and disease models. Researchers investigating muscle regeneration, sarcopenia, disuse atrophy, and hereditary myopathies use this reagent to track type IIX fiber shifts in tissue sections and protein lysates. Sodium azide in the storage buffer protects against microbial contamination; aliquots remain stable when stored refrigerated and protected from light. The polyclonal format provides epitope diversity, increasing the likelihood of detecting MYH1 even when a single linear epitope is masked or lost during fixation or sample processing.