Anti-MyD88 Antibody

This rabbit polyclonal antibody targets MyD88 (Myeloid Differentiation Primary Response 88), a cytosolic adapter protein that bridges activated Toll-like receptors and IL-1 family receptors to downstream IRAK kinases and NF-κB signaling.

Provided by Antibodies.com as an unconjugated polyclonal reagent, it is validated for western blot, immunohistochemistry, and ELISA workflows and cross-reacts with human, mouse, and rat samples. Researchers studying innate immune signaling, TLR pathway activation, cytokine-driven inflammation, and IRAK-mediated signal transduction use it to probe endogenous MyD88 levels in cell lysates and tissue sections.

Each vial contains 100 µl of affinity-purified antibody in a buffer suitable for standard immunodetection. Because it recognizes an epitope on the native adapter, it can support both denatured (western blot) and partially native (immunohistochemistry, ELISA) readouts, making it a versatile reagent for labs working across inflammation, host-defense, and signaling studies.