Anti-Myc (Ab-58) Antibody

Generated in rabbit as a polyclonal reagent and supplied at 100 µl in an unconjugated format, this Antibodies.com antibody recognizes the c-Myc transcription factor for research workflows in molecular and cellular biology. The reagent is validated for Western blot (WB) and immunohistochemistry (IHC), with confirmed reactivity against human, mouse, and rat samples, supporting studies in cancer biology, proliferation, apoptosis, and the characterization of Myc-tagged fusion proteins. Because the antibody is polyclonal, it binds multiple epitopes on the Myc target, which can help in detecting low-abundance protein in lysates or tissue sections. The unconjugated formulation gives flexibility to pair the reagent with HRP, biotin, or fluorescent secondary antibodies depending on the assay. Typical applications include confirming expression of transfected constructs carrying a Myc epitope tag by Western blot, profiling c-Myc distribution in tumor or normal tissue by IHC, and validating overexpression or knockdown effects in cell line models. Storage conditions and aliquoting recommendations from the supplier should be observed to maintain activity across repeated freeze-thaw cycles.