Anti-MYBPC2 Antibody

From Antibodies.com, this unconjugated rabbit polyclonal reagent was developed to detect MYBPC2, the fast-type isoform of myosin binding protein C expressed in Type II skeletal muscle fibers. The protein localizes to the sarcomeric thick filament, where it modulates cross-bridge cycling and helps stabilize the contractile apparatus during contraction. Investigators working on muscle fiber-type specification, exercise adaptation, and inherited myopathies commonly use MYBPC2 as a marker of fast-twitch fiber identity in human skeletal muscle tissue.

Supplied at 100 µl per vial in a liquid format, the antibody is validated for Western blot and immunofluorescence workflows against human samples. Because the reagent is polyclonal and raised in a rabbit host, it recognizes multiple epitopes on the target, giving robust signal amplification in cell lysates and in fixed tissue sections. For short-term handling, keep refrigerated; for longer-term storage, aliquot and freeze at -20°C and avoid repeated freeze-thaw cycles to preserve binding activity.