Anti-MYBPC1 Antibody

Raised in rabbit against the slow skeletal isoform of myosin-binding protein C, this polyclonal primary antibody from Antibodies.com is validated for Western blot detection of endogenous MYBPC1 in mouse and rat tissue lysates. The unconjugated IgG reagent is supplied as 200 µl of antiserum, supporting immunoblotting workflows that probe the sarcomeric thick-filament protein.

MYBPC1 is expressed predominantly in slow-twitch skeletal muscle fibers, where it contributes to thick filament stabilization and the regulation of cross-bridge cycling during contraction. Researchers studying neuromuscular development, sarcomere assembly, or MYBPC1-linked distal arthrogryposis myopathies use this reagent to evaluate endogenous protein levels in murine and rat slow-muscle preparations such as soleus and other type I fiber-rich tissues.

Host species is rabbit, clonality is polyclonal, and the conjugate is unconjugated. Reactivity is confirmed for mouse and rat samples only. The target protein migrates near 130 kDa on reducing SDS-PAGE. Handle the vial as a research-use-only reagent, aliquot upon first thaw, and store refrigerated to preserve polyclonal IgG activity across multiple experiments.