Anti-MYBBP1A Antibody

Antibodies.com provides a rabbit polyclonal antibody targeting MYBBP1A (Myb-Binding Protein 1A), a nucleolar transcriptional regulator implicated in p53-dependent stress responses, ribosome biogenesis, and chromatin remodeling. The unconjugated primary reagent is validated for Western blot and immunohistochemistry, enabling detection of the endogenous protein in human cell lysates and formalin-fixed tissue sections.

The polyclonal response recognizes multiple epitopes along the full-length MYBBP1A polypeptide, which concentrates in the nucleolus under homeostatic conditions and redistributes to the nucleoplasm during cellular stress. This reagent supports studies of transcription factor networks, nucleolar integrity, tumor suppressor signaling pathways, c-Myb co-regulation, and rRNA processing events.

Each vial contains 100 µl of antibody, providing ample material for repeated Western blot and immunohistochemistry experiments. Researchers should aliquot and freeze the reagent upon arrival to minimize freeze-thaw cycles and preserve binding activity; refrigerate working aliquots during ongoing experiments.