Anti-MYB Antibody

Raised in rabbit against the MYB transcription factor, this unconjugated polyclonal IgG reagent from Antibodies.com is supplied as 100 µl of liquid antiserum for Western blot and immunohistochemistry workflows. MYB (c-Myb) is a sequence-specific DNA-binding transcription factor best known for regulating hematopoietic stem and progenitor cell proliferation, T-cell development, and renewal of the colorectal crypt epithelium. Altered MYB activity is frequently studied in acute myeloid leukemia, T-ALL, and colorectal adenoma models, making validated detection antibodies valuable across both oncology and normal-tissue biology research.

Reported reactivity covers human and mouse samples, enabling cross-species expression profiling and tumor-tissue IHC alongside lysate-based WB confirmation of endogenous protein levels. For best results, aliquot upon receipt to limit freeze-thaw cycles and store refrigerated; the unconjugated format allows secondary-reagent flexibility for chromogenic IHC or chemiluminescent WB detection. Each lot is supplied as a single-use vial of 100 µl.