Anti-MVK Antibody

The Antibodies.com Anti-MVK polyclonal reagent is raised in rabbit and supplied as an unconjugated antibody preparation for researchers investigating mevalonate pathway biology. Mevalonate kinase (MVK) catalyzes the ATP-dependent phosphorylation of mevalonate to mevalonate-5-phosphate, an early committed step in isoprenoid and cholesterol biosynthesis, and the enzyme is also widely studied in connection with mevalonate kinase deficiency, an autoinflammatory disorder associated with elevated IL-1β signaling.

This Primary Antibodies reagent is validated for western blot and immunohistochemistry, with reactivity confirmed against human, mouse, and rat samples, making it useful across translational studies ranging from hepatic cholesterol metabolism to inflammatory disease models. The antibody is provided in a 100 µL vial; aliquot on arrival and store frozen for long-term stability, avoiding repeated freeze-thaw cycles, with short-term working aliquots kept refrigerated.