Anti-MUSK Antibody

Manufactured by Antibodies.com, this rabbit polyclonal reagent is raised against MUSK (muscle skeletal receptor tyrosine kinase) and is supplied as a 50 µl aliquot at a working concentration of 1.0 mg/mL. The antibody is unconjugated and has been purified by affinity chromatography using the immunogen, a recombinant human MUSK protein. It is validated for Western blot (WB) and immunohistochemistry (IHC) applications and is reported to detect the endogenous level of total MUSK protein in lysates and tissue sections prepared from human, mouse, and rat samples. The reagent belongs to the IgG isotype family and is formulated in phosphate-buffered saline (without Mg²⁺ and Ca²⁺) at pH 7.4, containing 150 mM NaCl, 0.02% sodium azide as a preservative, and 50% glycerol as a cryoprotectant; it is shipped at 4 °C and upon arrival should be aliquoted and stored at –20 °C, with repeated freeze/thaw cycles avoided to preserve binding activity. As a primary polyclonal antibody raised in rabbit, it is well suited for studies of neuromuscular junction biology, myasthenia gravis-related autoantibody research, and receptor tyrosine kinase signaling, where robust cross-species recognition of endogenous MUSK is required for reliable Western blotting and immunohistochemical detection in basic and translational neuroscience workflows.