Anti-MUSK Antibody

This rabbit-derived primary antibody recognizes MUSK (muscle-specific kinase), a receptor tyrosine kinase central to agrin–LRP4 signaling at the neuromuscular junction. Antibodies.com supplies the antibody as an unconjugated IgG preparation for Western blot workflows. Its reported reactivity covers both human and mouse MUSK, supporting comparative analysis of receptor expression in cell and tissue lysates.

The polyclonal format can provide recognition of multiple epitopes on the MUSK protein, while the unconjugated presentation allows laboratories to select a suitable labeled secondary antibody for their detection system. The antibody is relevant to research on neuromuscular-junction development, synaptic maintenance, and acetylcholine-receptor clustering.

The package contains 50 µl of antibody. As with other research antibodies, optimization of sample preparation, electrophoretic separation, blocking conditions, and secondary-antibody dilution is recommended for the specific Western blot protocol and detection chemistry used.