Anti-MUC1 Antibody [Assigned #A3619]

This mouse monoclonal IgG antibody from Antibodies.com targets MUC1 (Mucin 1), a heavily O-glycosylated transmembrane glycoprotein widely studied as a tumor-associated antigen in epithelial carcinomas. Produced in mouse hosts and supplied unconjugated in a 100 µl vial, the reagent is validated for western blot detection of human MUC1 in cell lysate and tissue-derived samples. Researchers investigating breast, pancreatic, ovarian, and colorectal carcinomas routinely probe for MUC1 overexpression by immunoblotting, since the aberrantly glycosylated tumor form differs markedly in apparent molecular weight from the isoform expressed in healthy glandular epithelium.

As an unconjugated IgG reagent with confirmed reactivity against human MUC1, this antibody can be paired with the user's preferred HRP-conjugated or fluorescent secondary reporter and integrated directly into existing western blot workflows without buffer reformulation. Each vial contains sufficient material for multiple immunoblot experiments against epithelial cell lines and patient-derived tumor lysates. The IgG isotype background simplifies selection of compatible secondary antibodies such as goat anti-mouse IgG-HRP, supporting reproducible chemiluminescent readouts of the variable-number tandem repeat region and the cytoplasmic tail of MUC1 on standard PVDF or nitrocellulose membranes.