Anti-mTOR (phospho S2448) Antibody

A rabbit polyclonal IgG antibody from Antibodies.com that specifically recognizes the mechanistic Target of Rapamycin (mTOR) only when phosphorylated at Serine 2448, a site linked to Akt-dependent kinase signaling and downstream control of cell growth, proliferation, and autophagy. The unconjugated antibody is supplied as a 50 µl vial and is validated for western blot, immunohistochemistry, and immunofluorescence workflows on human samples. Researchers investigating PI3K/Akt/mTOR pathway activation, oncogenic signaling in tumor tissues, or nutrient-sensing responses in cell culture models use this reagent to monitor activation-state changes that total mTOR antibodies cannot distinguish. The phospho-specific epitope allows discrimination of active versus inactive kinase pools in signaling studies. Store at -20°C in working aliquots to limit freeze-thaw cycles, and protect from light during handling.