Anti-mTOR Antibody

Raised in rabbit against the mTOR kinase, this unconjugated IgG polyclonal reagent from Antibodies.com is supplied at 100 µl and validated for western blot, immunohistochemistry, and immunofluorescence workflows on human samples. mTOR (mechanistic Target of Rapamycin) sits at the core of the PI3K/AKT signaling axis and assembles into two distinct multiprotein complexes, mTORC1 and mTORC2, that govern protein synthesis, autophagy, cell growth, and survival. Researchers investigating nutrient sensing, growth factor signaling, tumor cell proliferation, metabolic disease, and neurodegeneration routinely use anti-mTOR antibodies to probe phosphorylation events on downstream effectors such as p70S6K, 4E-BP1, and Akt. The unconjugated format leaves the antibody free for direct coupling to HRP, biotin, or fluorophores of the user's choice, supporting flexible assay design across fixed tissue sections and cultured cell lines. Aliquot upon arrival and store refrigerated to preserve performance across repeated freeze-thaw cycles; the polyclonal profile broadens epitope coverage and improves detection of the ~289 kDa target across denaturing and native preparations.