Anti-MTDH Antibody

Raised in rabbit, this unconjugated polyclonal antiserum from Antibodies.com targets metadherin (MTDH), a single-pass transmembrane oncoprotein frequently studied in hepatocellular carcinoma, breast cancer, and glioblastoma research. The antigen is recognized across human, mouse, and rat samples, supporting comparative work in xenograft, knockout, and patient-derived tissue studies. Supplied as a 100 µl liquid stock at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, the antibody is formulated for direct use in Western blot and immunohistochemistry workflows without further dilution in most standard protocols. The polyclonal composition increases the likelihood of binding even when MTDH is post-translationally modified or partially degraded during sample preparation, which is useful when probing archival formalin-fixed tissue. Researchers investigating NF-κB signaling, PI3K/AKT pathway activation, or metastasis-associated gene programs often use MTDH as a marker due to its documented role as a downstream effector of c-Myc and Ha-ras.