Anti-MTCH2 Antibody

MTCH2 (Mitochondrial carrier homolog 2) is a 33 kDa outer-mitochondrial-membrane insertase that has emerged as a key regulator of BAX/BAK-dependent apoptotic pore assembly, mitochondrial lipid handling, and metabolic disease phenotypes including obesity and Alzheimer's. This unconjugated rabbit polyclonal IgG reagent from Antibodies.com is supplied as a 200 µl vial of liquid antibody and binds endogenous MTCH2 in both fixed tissue sections and detergent-lysed cell preparations. It is validated for western blot and immunohistochemistry on human and mouse samples, producing a clean band that pairs readily with a rabbit-specific HRP- or fluorophore-conjugated secondary antibody. Researchers studying T-cell biology, mitochondrial outer-membrane permeabilization, MFN2-dependent mitochondrial fusion, or cGAS-STING activation downstream of mtDNA release use this reagent to track MTCH2 levels across wild-type, knockout, and rescue systems. Store frozen at -20 °C in working aliquots to limit freeze-thaw cycles and preserve antibody activity across multiple experiments.