Anti-MTA3 Antibody

This polyclonal reagent specifically targets MTA3, a chromatin-associated subunit of the Mi-2/NuRD nucleosome remodeling and histone deacetylase complex. MTA3 contributes to transcriptional regulation and plays documented roles in epithelial-mesenchymal transition, B-cell maturation, and estrogen receptor signaling pathways linked to breast cancer biology.

Provided by Antibodies.com as an unconjugated rabbit IgG polyclonal antibody in a 50 µL volume, the reagent is validated for western blot and immunohistochemistry across human, mouse, and rat samples. Polyclonal recognition of multiple epitopes supports reliable detection in immunoblotting of cell and tissue lysates and in localization studies on fixed tissue sections.

Typical research uses span chromatin remodeling investigations, miRNA-mediated gene regulation studies, and MTA family signaling analyses in metastasis models. The antibody serves chromatin biology, oncology, and developmental research applications.