Anti-MT-ND2 Antibody

MT-ND2 (NADH-ubiquinone oxidoreductase chain 2) is a core catalytic subunit of mitochondrial Complex I, the entry-point enzyme of the oxidative phosphorylation electron transport chain. This rabbit polyclonal antibody from Antibodies.com binds MT-ND2 and has been validated for Western blot detection in human, mouse, and rat samples.

The unconjugated reagent is supplied as a 100 µl aliquot at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, a storage buffer that maintains antibody stability across multiple freeze-thaw cycles. Sodium azide serves as a preservative against microbial contamination, and the 50% glycerol cryoprotectant prevents ice-crystal damage during long-term storage.

MT-ND2 expression levels serve as a biomarker for mitochondrial biogenesis and Complex I assembly in studies of metabolic disorders, neurodegeneration, and oxidative stress. Cross-reactivity across human, mouse, and rat species supports translational research programs and preclinical animal model investigations of mitochondrial dysfunction. Each vial provides enough reagent for multiple Western blot experiments using standard immunoblotting protocols and standard chemiluminescent or colorimetric detection chemistries on nitrocellulose or PVDF membranes.