Anti-MT-CO2 Antibody

MT-CO2 is the mitochondrially encoded catalytic subunit II of cytochrome c oxidase, the respiratory complex IV that reduces oxygen and powers the electron transport chain. Because the gene resides in mitochondrial DNA rather than the nucleus, MT-CO2 levels are widely used as a readout of mitochondrial biogenesis, oxidative phosphorylation activity, and mitochondrial translation in research on neurodegeneration, metabolic disease, aging, and tumor metabolism.

From Antibodies.com, this rabbit polyclonal antibody recognizes MT-CO2 and is supplied as an unconjugated reagent in a 100 µl volume. It is validated for western blot and immunohistochemistry workflows and reacts with both human and mouse samples, supporting cross-species studies of complex IV assembly, respiratory chain function, and mitochondrial content.

The polyclonal format offers recognition of multiple epitopes across the MT-CO2 protein, which is useful when probing denatured lysates or fixed tissue sections where a single epitope may be masked. Delivered unconjugated, the antibody pairs with any user-selected reporter, fluorophore, secondary antibody, or chromogen suited to a chosen detection platform, and is intended for research use only.