Anti-MSK1 (Ab-212) Antibody

Rabbit polyclonal antibody from Antibodies.com targeting MSK1 (Mitogen- and Stress-activated Kinase 1, gene name RPS6KA5) when phosphorylated at threonine 212, a residue within the kinase activation loop whose modification by ERK1/2 or p38 MAPK is required for full enzymatic activity.

Each vial contains 100 µL of unconjugated, affinity-purified antisera, validated for western blot and immunohistochemistry on human and mouse specimens. The reagent enables detection of activated MSK1 in whole-cell lysates, nuclear extracts, and formalin-fixed tissue sections, supporting research on stress, mitogenic, and inflammatory signaling cascades that converge on chromatin remodeling and immediate-early gene transcription.

As an unconjugated primary antibody, it pairs readily with standard HRP-conjugated or fluorescent secondary reagents, allowing flexible chemiluminescent, colorimetric, or immunofluorescence readouts for research use only workflows.