Anti-MSH3 Antibody

A rabbit polyclonal primary antibody targeting MutS Homolog 3 (MSH3), a core component of the DNA mismatch repair pathway that forms the MutSβ heterodimer with MSH2 and binds insertion-deletion loop mismatches during repair. Manufactured by Antibodies.com as an unconjugated reagent at 1 mg/ml in PBS buffer containing 0.1% sodium azide and 50% glycerol, it is validated for Western blot (WB) and immunohistochemistry (IHC) on human tissue and cell lysates. The 100 µl pack size supports multiple gel runs or stained slides per experiment.

Researchers studying microsatellite instability, Lynch syndrome genetics, and mismatch repair deficiency in colorectal, endometrial, and other tumors use MSH3 antibodies to probe protein expression patterns. The polyclonal format offers recognition of multiple epitopes across the MSH3 protein, helping distinguish full-length expression from truncated isoforms. Store refrigerated and protect from light; the glycerol-containing buffer tolerates standard short-term handling without aliquoting for typical Western blot workflows.