Anti-MSH2 Antibody

MSH2 (MutS Homolog 2) is a core component of the DNA mismatch repair (MMR) machinery, and this unconjugated polyclonal IgG reagent from Antibodies.com is raised in rabbit against the human protein for research use. The antibody is validated for Western blot, immunofluorescence, and flow cytometry, supporting monitoring of MSH2 expression, nuclear localization, and heterodimer assembly with MSH6 or MSH3 in human cells. It enables studies of Lynch syndrome (hereditary nonpolyposis colorectal cancer) and other mismatch repair-deficient tumors where MSH2 loss contributes to microsatellite instability. Supplied as 200 µl of polyclonal antibody in vial format, the unconjugated design allows laboratories to pair it with their preferred secondary labels for chromogenic or multiplex fluorescence detection.