Anti-MS4A12 Antibody

The MS4A12 protein (Membrane-Spanning 4-Domains Subfamily A Member 12) is a tetraspan family member localized primarily to the apical surface of colonic epithelial cells, where altered expression has been linked to colorectal adenocarcinoma and intestinal differentiation studies. This rabbit polyclonal IgG reagent from Antibodies.com is raised against human MS4A12 and validated for western blot detection of the endogenous target in lysates prepared from human cell lines or tissue samples. Supplied as an unconjugated preparation in a 100 µl vial, the antibody is affinity-purified from rabbit serum and contains no fluorophore, biotin, or enzyme label, giving researchers flexibility to pair it with their preferred anti-rabbit secondary reagent for chemiluminescent or fluorescent western blot workflows. The polyclonal format targets multiple epitopes across the MS4A12 antigen, which can produce a stronger signal in denatured and reduced lysate preparations than a monoclonal alternative restricted to a single epitope. Investigators studying gastrointestinal epithelium biology, colorectal cancer biomarker panels, or MS4A family expression profiling in human cohorts will find this reagent useful for probing endogenous levels of the target. Store refrigerated at 4°C and protect from light to maintain reagent stability; aliquot on first use to limit repeated freeze-thaw cycles. Intended for research use only.