Anti-MRPS27 Antibody

Raised in rabbit against the human MRPS27 mitochondrial ribosomal protein, this unconjugated polyclonal IgG reagent from Antibodies.com is supplied as 100 µl of affinity-purified antiserum and is validated for western blot, immunohistochemistry, immunofluorescence, and immunoprecipitation. MRPS27 is an RNA-binding component of the small 28S subunit of the mammalian 55S mitoribosome (UniProt Q92552), producing a mature polypeptide of approximately 47 kDa after cleavage of its N-terminal mitochondrial targeting sequence. The antibody recognizes an internal epitope on MRPS27, which stimulates mitochondrial mRNA translation of oxidative phosphorylation subunits and binds the 12S rRNA within the ribosomal complex; the reagent cross-reacts with mouse and rat orthologs and is intended for research use only in studies of mitochondrial translation, respiratory chain biogenesis, and tumor cell proliferation. Store the vial refrigerated, aliquot on receipt, and limit freeze-thaw cycles to preserve polyclonal activity across repeated experiments.