Anti-MRPS18C Antibody

The target MRPS18C (Mitochondrial Ribosomal Protein S18C) is a structural component of the 28S small subunit of the mammalian mitochondrial ribosome, where it supports translation of the 13 mitochondrially encoded oxidative phosphorylation subunits. This unconjugated rabbit polyclonal reagent from Antibodies.com is raised against MRPS18C and validated for Western blot (WB), immunohistochemistry (IHC), and immunofluorescence (IF) applications in human and mouse samples.

The antibody is supplied as 100 µl of polyclonal antiserum. As a polyclonal reagent, it recognizes multiple epitopes across the target, which can improve tolerance for minor sequence variation between human and mouse orthologs and supports consistent detection of endogenous MRPS18C across Western blot membranes, fixed tissue sections, and immunofluorescence preparations. The unconjugated format allows the antibody to be paired with secondary reagents matched to a chosen detection chemistry, including HRP, alkaline phosphatase, or fluorescent conjugates.

MRPS18C has attracted research interest in studies of mitochondrial translation, ribosome biogenesis, and reported extra-ribosomal functions linking its expression to cell-cycle control and tumor biology. For handling, aliquotting the antibody into working volumes is recommended to limit repeated freeze-thaw cycles of the stock. The reagent is supplied for research use only and is not intended for diagnostic procedures.