Anti-MRPS16 Antibody

MRPS16 encodes a nuclear-encoded structural component of the small 28S subunit of the human mitochondrial ribosome, where it supports translation of the 13 mitochondrially-encoded electron transport chain subunits. This unconjugated rabbit polyclonal IgG reagent from Antibodies.com is supplied as a 100 µl single use vial and has been validated for Western blot detection of the endogenous protein in human, mouse, and rat lysates. Researchers investigating mitochondrial translation disorders, oxidative phosphorylation complex assembly, and ribosomal biogenesis apply it to probe complex I–V subunit expression in cell and tissue samples. Biallelic variants in MRPS16 have been linked to combined oxidative phosphorylation deficiency, making dependable immunodetection useful for characterizing affected patient cells and disease models. The antibody is hosted in rabbit and is reactive across three species commonly used in metabolic and neurological research. Aliquot upon arrival and store at -20°C, avoiding repeated freeze-thaw cycles to preserve binding activity. Research use only.