Anti-MRPL11 Antibody

MRPL11 (Mitochondrial Ribosomal Protein L11) is a structural component of the large 39S subunit of the mammalian mitochondrial ribosome, where it supports mitochondrial translation. This polyclonal antibody from Antibodies.com is raised in rabbit and targets the human MRPL11 antigen, validated for Western Blot, Immunohistochemistry, and Immunofluorescence workflows on human samples.

Supplied as 100 µl of unconjugated antiserum, the reagent enables probing of mitochondrial ribosome biogenesis and translation in cell lysates, fixed cells, cryosections, and paraffin-embedded tissues. MRPL11 serves as a marker of the mitochondrial large ribosomal subunit, and researchers apply this antibody in studies of oxidative phosphorylation, mitochondrial disorders, neurodegeneration, metabolic syndromes, and cancers where mitochondrial reprogramming is implicated.

The unconjugated format permits flexible secondary labeling with fluorophores, horseradish peroxidase, or biotin depending on the detection platform. Endogenous MRPL11 expression, assessed by Western Blot, Immunofluorescence, or Immunohistochemistry, offers a readout of mitochondrial content and translational capacity under varied experimental and pathological conditions.