Anti-MRP-S34 Antibody

Raised in rabbit against mitochondrial ribosomal protein S34, this unconjugated polyclonal reagent from Antibodies.com is supplied in a 100 µl vial and validated for western blot and ELISA workflows. It cross-reacts with both human and mouse samples, supporting translational research on mitochondrial translation, oxidative phosphorylation, and metabolic disease.

MRP-S34 is a structural component of the 28S small subunit of the mammalian mitochondrial ribosome, where it contributes to the synthesis of mitochondrially encoded proteins of the electron transport chain. Because the target is mitochondrial rather than cytosolic, researchers commonly pair this antibody with organelle-enrichment protocols and load mitochondrial lysates alongside cytosolic controls to confirm specificity. The polyclonal format recognizes multiple epitopes on the protein, which is useful when probing endogenous fractions or tracking expression changes under metabolic stress. The unconjugated format leaves the reagent compatible with secondary-labelled detection chemistries (HRP, fluorophore, or biotin), so it can be incorporated into standard immunoblotting or plate-based detection pipelines.

Typical use begins with a working dilution titration on a positive control lysate expressing MRP-S34, with western blot detection expected near the predicted molecular weight of the mature mitochondrial protein. This reagent is intended for research use only.