Anti-MRP-S21 Antibody

MRPS21 is a structural component of the small 28S subunit of the mitochondrial ribosome, contributing to mitochondrial translation of oxidative phosphorylation complexes. This unconjugated rabbit polyclonal reagent from Antibodies.com is supplied as a 50 µl vial and is validated for western blot, immunohistochemistry, immunofluorescence, and ELISA applications. The antibody cross-reacts with the human, mouse, rat, and monkey orthologs, enabling comparative studies of mitochondrial ribosome assembly and dysfunction across model systems.

Investigators examining mitochondrial translation defects, OXPHOS deficiency, or mitochondrial disease mechanisms use this reagent in conjunction with cell culture lysates and tissue sections to track MRPS21 protein expression. Standard handling includes aliquoting upon receipt to reduce freeze-thaw cycles, keeping working dilutions refrigerated for short-term use, and storing frozen for extended periods to maintain activity. Polyclonal reactivity against multiple epitopes on the MRPS21 target can aid detection of processed variants in research use only workflows.