Anti-MRP-S21 Antibody

Rabbit polyclonal antibody raised against MRPS21, the mitochondrial ribosomal protein S21 that forms part of the 28S small subunit of the mammalian mitochondrial ribosome and supports translation of mitochondrially encoded oxidative phosphorylation components. This unconjugated reagent from Antibodies.com is supplied as 100 µl of polyclonal antibody and is validated for use in western blot, immunohistochemistry, immunofluorescence, and ELISA workflows across human, mouse, rat, and monkey samples.

MRPS21 is required for accurate assembly and function of the mitochondrial translation machinery; alterations in MRPS21 expression have been reported in studies of mitochondrial disease and altered oxidative phosphorylation capacity. Researchers investigating mitochondrial ribosome biogenesis, mitochondrial translation, or mitochondrial disorders use this reagent to probe MRPS21 in cell lines, tissue sections, and primary isolates. The polyclonal format allows recognition of multiple epitopes on the target protein, which can be useful when probing cleavage products or alternate conformers during western blot analysis.

Storage recommendations: refrigerate the antibody for short-term use and aliquot for long-term storage at -20°C to preserve activity across freeze-thaw cycles. Avoid repeated freeze-thaw of the working stock. The unconjugated format leaves the antibody available for downstream conjugation, including custom labelling for immunofluorescence detection or affinity purification of MRPS21-containing complexes.