Anti-MRP-S12 Antibody

Produced in rabbit and supplied unconjugated, this polyclonal reagent from Antibodies.com binds MRP-S12, a nuclear-encoded component of the 28S subunit of the mammalian mitoribosome that is imported into the mitochondrial matrix. Validated for Western blot and reactive against human, mouse, and rat samples, the antibody supports comparative studies of mitochondrial translation and ribosome assembly across species.

The 100 µl format is provided at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, a cryoprotective buffer that allows aliquoting and storage at -20 degrees C with minimal freeze-thaw cycling. The polyclonal format gives multi-epitope recognition of the S12 target, helping to detect both full-length and processed forms in mitochondrial lysates and subcellular fractions. Researchers working on OXPHOS complex assembly, mitochondrial disease models, or mitochondrial protein synthesis commonly use this reagent to probe steady-state levels of the small mitoribosomal subunit in cell lines and primary tissue.