Anti-MRCKB Antibody

Targeting the serine/threonine kinase CDC42-binding kinase beta, this polyclonal antibody from Antibodies.com supports research into cytoskeletal remodeling and actomyosin contractility.

The unconjugated rabbit reagent is supplied in a 100 µl volume and is validated for Western blot and immunohistochemistry detection of MRCKB in human, mouse, and rat samples.

MRCKB phosphorylates myosin light chain and coordinates actin stress fiber assembly, focal adhesion turnover, and cell migration, and is studied in the context of epithelial morphogenesis, tumor cell invasion, wound healing responses, and neuronal growth-cone dynamics.

Because the antibody is unconjugated, investigators can pair it with HRP, biotin, or fluorophore-conjugated secondary reagents to match specific detection chemistries, including colorimetric immunoblotting, chromogenic IHC on formalin-fixed paraffin-embedded sections, and immunofluorescence imaging of contractile structures.

For storage, aliquot the reagent upon arrival and store at -20 °C to preserve activity, avoiding repeated freeze-thaw cycles; refrigerate for short-term active handling.