Anti-Moesin / Ezrin / Radixin Antibody

This Rabbit polyclonal antibody from Antibodies.com targets the conserved C-terminal domain shared by Moesin, Ezrin, and Radixin, three members of the ERM (Ezrin-Radixin-Moesin) family of membrane-organizing proteins that link the actin cytoskeleton to the plasma membrane. Raised in Rabbit and supplied as 100 µl of unconjugated antiserum, the reagent is validated for Western blot, immunohistochemistry, and ELISA workflows across Human, Mouse, and Rat sample types.

Because of the strong sequence homology between the ERM paralogs, the polyclonal reagent recognizes all three proteins on the same blot or section, which is useful when comparing their relative expression in studies of cell adhesion, microvilli formation, immune synapse organization, and cytoskeletal remodeling. Recommended handling includes brief centrifugation of the vial after thawing, division into single-use working aliquots to limit freeze-thaw cycles, and pairing with HRP- or fluorophore-conjugated secondary antibodies for signal detection in WB and IHC.