Anti-MOB1A Antibody

MOB1A is a core component of the Hippo tumor suppressor signaling pathway, where it acts as a phosphorylation-dependent co-activator of the LATS1 and LATS2 kinases that restrain YAP/TAZ-driven transcription. This unconjugated rabbit polyclonal reagent from Antibodies.com is raised against the human MOB1A target and cross-reacts with mouse and rat orthologs, supporting comparative studies across model systems and tumor specimens. Validated for western blot and immunohistochemistry workflows, the antibody is supplied as a 100 µl liquid aliquot and is intended for research use only. Applications include kinase pathway analysis, subcellular localization studies in fixed tissue sections, and protein expression profiling in cancer cell lines. Its polyclonal format increases the chance of detecting MOB1A across multiple epitopes, which is useful when working with phospho-states or truncated variants encountered in Hippo-pathway investigations of organ size control, contact inhibition, and oncogenic transformation.