Anti-Mnk1 (I136) Antibody

Raised in rabbit against a defined internal epitope of human Mnk1 (also known as MKNK1), this polyclonal antibody from Antibodies.com targets a serine/threonine kinase that operates downstream of ERK and p38 MAP kinases and phosphorylates the cap-binding translation initiation factor eIF4E on Ser209. Researchers studying cap-dependent translation initiation, MAPK-coupled signaling, and the contribution of Mnk1 to oncogenic transformation, stress responses, or inflammatory signaling routinely monitor endogenous kinase levels with this reagent across cellular and tissue model systems.

The antibody is supplied unconjugated at 1 mg/ml in 50 µl of phosphate buffered saline (PBS) with 0.05% sodium azide at approximately pH 7.2, and is validated for Western blot and immunohistochemistry on human, mouse, and rat samples. The polyclonal format recognizes multiple epitopes on Mnk1, which is helpful when examining phosphorylation-dependent mobility shifts or comparing Mnk1 expression across tissues. Store refrigerated; sodium azide acts as a preservative. For research use only.