Anti-Mnk1 Antibody

Mnk1 (MAP kinase-interacting serine/threonine-protein kinase 1) is a downstream effector of the MAPK signaling cascade, phosphorylating eukaryotic initiation factor 4E (eIF4E) at Ser209 to control cap-dependent mRNA translation. Antibodies.com provides this rabbit polyclonal anti-Mnk1 reagent for researchers studying translational regulation, mitogenic signaling, and stress-activated kinase pathways.

The unconjugated antibody is supplied as 100 µl of liquid, raised in rabbit against the Mnk1 target, and validated for western blot, immunohistochemistry, and ELISA workflows. Reactivity covers human and mouse samples, supporting experiments on patient-derived cell lines, primary cultures, or standard murine models.

Mnk1 activity is implicated in oncogenic translation programs, inflammatory cytokine responses, and synaptic plasticity, so the reagent is useful in cancer biology, immunology, and neuroscience research. Researchers can monitor expression across treated versus untreated conditions, map subcellular localization in fixed tissue sections, or probe Mnk1 levels in lysates and conditioned media. The polyclonal format recognizes multiple epitopes on Mnk1, increasing the chance of detecting the target across species and isoforms.

Best practice is to aliquot the vial upon arrival, limit freeze-thaw cycles, and store refrigerated between uses to preserve antibody activity over time.