Anti-MMS19 Antibody

Raised in rabbits against the cytosolic iron-sulfur assembly component MMS19, this polyclonal IgG reagent from Antibodies.com is supplied as a 50 µl liquid aliquot in a single vial. The unconjugated antibody is validated for Western blot detection of the mouse target, supporting studies of the cytosolic iron-sulfur protein assembly (CIA) targeting complex. Within this complex, MMS19 functions as an adapter linking early-acting CIA factors such as CIAO1 and MIP18 with downstream Fe-S apoproteins including ERCC2/XPD, FANCJ and RTEL1, thereby connecting cytosolic cluster loading to nuclear DNA metabolism. The reagent is suited for probing nucleotide excision repair, DNA replication, telomere maintenance, chromosome segregation and broader Fe-S biogenesis pathways in mouse samples. Intended for research use only, it provides a tool for investigating CIA complex composition, MMXD-associated mitotic functions, and genome-stability mechanisms.