Anti-MMRN1 Antibody

Raised in rabbit against human Multimerin 1 (MMRN1), this polyclonal reagent from Antibodies.com targets a large soluble glycoprotein that is stored in platelet α-granules and the Weibel-Palade bodies of vascular endothelial cells. MMRN1 functions as the principal carrier protein for platelet factor V and factor Va and has been studied in the context of vascular biology, megakaryocyte biology, and inherited bleeding disorders such as the autosomal thrombocytopenia locus on chromosome 4q.

Provided at 1 mg/ml in PBS containing 0.1% sodium azide and 50% glycerol, the antibody is supplied as a 50 µl aliquot and is unconjugated, allowing flexible pairing with secondary detection reagents. It is validated for Western blot, immunohistochemistry, and immunofluorescence on human samples, supporting studies of endothelial activation, platelet release, and thrombin generation pathways.

Researchers working on coagulation factor storage, von Willebrand factor co-localization, or endothelial marker panels will find this reagent useful for probing MMRN1 expression across cultured endothelial cells, platelet lysates, and formalin-fixed tissue sections. Storage at -20 °C with minimal freeze-thaw cycles is recommended to preserve activity, and the glycerol-containing buffer protects the antibody from damage during routine handling.