Anti-MMP15 Antibody

Matrix metalloproteinase 15 (MMP15), also termed MT2-MMP, is a membrane-anchored endopeptidase that cleaves extracellular matrix substrates and contributes to tumor invasion, pericellular proteolysis, and tissue remodeling. This polyclonal rabbit IgG antibody from Antibodies.com is raised against MMP15 and validated for Western blot detection of endogenous protein in human, mouse, and rat samples. The unconjugated reagent is supplied as 100 µl per vial, enabling direct use in standard immunoblotting protocols on whole-cell lysates or membrane-enriched fractions. Researchers apply this reagent to investigate MT-MMP activation, processing of the zymogen to its catalytically active form, and MMP15 expression changes in cancer cell migration assays, fibrotic disease models, and angiogenesis studies. Its cross-reactivity profile across three species makes it suitable for comparative work in murine xenograft systems and rodent disease models alongside human tissue analysis.