Anti-MMP-7 Antibody

Targeted against MMP-7 (matrilysin, also known as PUMP-1), this unconjugated rabbit polyclonal antibody from Antibodies.com is supplied as 100 µl of reagent validated for Western blot and immunohistochemistry workflows.

MMP-7 is the smallest secreted member of the matrix metalloproteinase family, a zinc-dependent endopeptidase that cleaves extracellular matrix substrates such as fibronectin, laminin, elastin, and entactin, and activates pro-MMP-2 and pro-MMP-9 to amplify pericellular proteolysis. The reagent was raised in rabbit and recognizes the endogenous MMP-7 target in human, mouse, and rat samples, supporting cross-species investigation of epithelial repair, mucosal inflammation, and tumor invasion biology.

Investigators apply this antibody to characterize MMP-7 expression in colorectal, pancreatic, gastric, and breast carcinoma tissue sections, alongside studies of inflammatory bowel disease, lung injury, and wound remodeling models. Polyclonal reactivity broadens epitope coverage on the mature and zymogen forms of the target, while the unconjugated format lets researchers pair the reagent with their preferred reporter or label system.

Store refrigerated and protect from light; avoid repeated freeze-thaw cycles to preserve antibody activity.