Anti-MMP-3 Antibody

Matrix metalloproteinase-3 (MMP-3), also called stromelysin-1, is a zinc-dependent endopeptidase that cleaves extracellular matrix components including fibronectin, laminin, and several collagen subtypes, and it activates other latent matrix metalloproteinases at sites of tissue remodeling. This rabbit polyclonal antibody from Antibodies.com is supplied as 100 µl of unconjugated antiserum validated for western blot and immunohistochemistry workflows. The reagent detects endogenous MMP-3 in human, mouse, and rat samples, supporting cross-species studies of cartilage turnover, joint remodeling, and tumor microenvironment research. For long-term storage, aliquot the vial and freeze at -20 °C, avoiding repeated freeze-thaw cycles that can degrade antibody titer. Researchers commonly apply this reagent to investigate MMP-3 expression in arthritis models, cancer invasion assays, and inflammatory tissue sections where elevated stromelysin activity contributes to pathology.