Anti-MMP-19 Antibody

This rabbit polyclonal antibody targets matrix metalloproteinase 19 (MMP-19), a zinc-dependent endopeptidase that participates in extracellular matrix turnover, basement membrane remodeling, and the proteolytic processing of chemokines, growth factors, and adhesion molecules. Supplied by Antibodies.com as a 100 µl unconjugated preparation, the reagent is validated for Western blot, immunohistochemistry, and ELISA workflows with reactivity confirmed in human and mouse samples.

Raised against recombinant MMP-19 immunogen, this polyclonal reagent recognizes multiple epitopes on the target protein, which is helpful when probing both full-length and processed forms of MMP-19 in cell lysates and fixed tissue sections. MMP-19 expression has been reported in keratinocytes, synovial fibroblasts, vascular smooth muscle cells, placental trophoblasts, and several carcinoma cell lines, where it has been linked to angiogenic switching, cell migration, and inflammatory cell recruitment. The antibody therefore supports research into wound healing, joint remodeling in arthritic disease models, tumor microenvironment characterization, and matrix turnover in fibrotic conditions.

For storage, keep the vial refrigerated and aliquot upon first use to minimize repeated freeze-thaw cycles of the stock solution. The unconjugated format allows flexibility in choosing enzyme, fluorophore, or biotin labels for downstream detection. Researchers studying matrix biology, cancer invasion mechanisms, or chronic inflammatory pathways can incorporate this reagent into cell culture experiments, tissue section analysis, and quantitative immunoassays.