Anti-MMP-14 Antibody

This rabbit polyclonal antibody from Antibodies.com targets MMP-14 (matrix metalloproteinase-14, also called MT1-MMP), a membrane-anchored enzyme that cleaves extracellular matrix components and drives pericellular proteolysis. The unconjugated reagent is supplied as a 100 µl liquid aliquot and has been validated for Western blot (WB) and immunohistochemistry (IHC) workflows using human, mouse, and rat samples.

Investigators studying tumor cell invasion, angiogenic sprouting, or fibrotic matrix turnover rely on MMP-14 detection to map enzyme expression at the cell surface and within tissue sections. Because the reagent is polyclonal, it recognizes multiple epitopes across the target, which supports robust signal in both denatured lysate blots and formalin-fixed paraffin-embedded tissue preparations.

For best stability, the antibody should be stored refrigerated and partitioned into single-use aliquots to limit freeze-thaw cycles, with protection from light during handling. The product is intended for research use only.