Anti-MMP-13 Antibody

MMP-13 (matrix metalloproteinase 13), also called collagenase-3, is a zinc-dependent endopeptidase that cleaves type II collagen and other extracellular matrix components, making it a central marker in studies of cartilage turnover, osteoarthritis progression, and tumor invasion. This unconjugated rabbit polyclonal reagent from Antibodies.com is raised against human MMP-13 and supports western blot, immunohistochemistry, immunofluorescence, and ELISA workflows on human samples.

Each vial is supplied as 100 µl of liquid antiserum suitable for multiple blotting or staining experiments. For best stability, aliquot upon arrival and store at -20 °C; avoid repeated freeze-thaw cycles, and protect from light to preserve antibody activity. The polyclonal format broadens epitope coverage across pro- and processed species of the enzyme, which is useful when probing cleaved MMP-13 fragments in synovial fluid, cartilage explants, or cultured chondrocytes.

Researchers investigating joint degeneration, bone remodeling, or metastatic cancer biology will find this Antibodies.com reagent a practical choice for tracking MMP-13 expression at the protein level across tissue sections and lysates.