Anti-MMP-11 Antibody

Matrix metalloproteinase 11 (MMP-11), also known as stromelysin-3, is a zinc-dependent endopeptidase expressed during embryonic development and reactivated in invasive carcinomas, where it contributes to extracellular matrix remodeling and tumor progression. Antibodies.com provides a polyclonal rabbit antibody raised against this target, supplied as a 100 µl aliquot of unconjugated reagent validated for western blot, immunohistochemistry, immunofluorescence, and ELISA workflows.

The reagent cross-reacts with human, mouse, and rat MMP-11, supporting cancer metastasis, fibrotic disease, and developmental biology studies across multiple model systems. As a polyclonal reagent, it binds multiple epitopes on both the proenzyme and processed catalytic forms of MMP-11, enabling detection in cell lysates, paraffin-embedded tissue sections, and fixed specimens.

To preserve binding activity across experiments, store aliquots and limit freeze-thaw cycles. Each vial is provided unconjugated, allowing direct integration into custom western blot, immunohistochemistry, and immunofluorescence protocols.