Anti-MLL5 Antibody

This primary antibody from Antibodies.com targets MLL5 (Mixed Lineage Leukemia 5, also called KMT2E), a histone lysine methyltransferase involved in chromatin modification, transcriptional regulation, and hematopoiesis. Raised in rabbit and purified as a polyclonal reagent, the antibody is supplied unconjugated in a 100 µl vial, accommodating diverse secondary labels and detection chemistries chosen by the user.

Validated for Western blot and immunofluorescence applications, the reagent detects endogenous MLL5 across human, mouse, and rat samples. Investigators use it to examine MLL5-dependent processes including cell cycle progression, retinoic acid signaling, leukemogenesis, and chromatin remodeling at H3K4 methylation sites. Storage at -20 °C in small working aliquots is recommended to preserve activity through repeated freeze-thaw cycles, and the unconjugated format suits chromogenic, fluorescent, and HRP-based detection when paired with an appropriate secondary antibody.