Anti-MLF1 Antibody

This rabbit polyclonal IgG reagent from Antibodies.com is raised against myeloid leukemia factor 1 (MLF1), a ~27 kDa cytoplasmic protein originally identified through its involvement in the t(3;5)(q25;q34) translocation associated with acute myeloid leukemia. The unconjugated antibody is supplied as 100 µl of liquid and is validated for Western blot detection of endogenous MLF1 in human and mouse samples, supporting studies of hematopoietic differentiation, NPM1-MLF1 fusion biology, and 14-3-3-mediated signaling pathways linked to leukemogenesis and solid tumor progression. Because MLF1 expression is frequently deregulated in myelodysplastic syndromes and certain carcinomas, the reagent enables researchers to probe steady-state protein levels and subcellular distribution in lysates prepared from cultured lines or primary tissue. Aliquot upon first use and store refrigerated to preserve polyclonal titer across repeated experiments.