Anti-MKK7/MAP2K7 Antibody

Produced in rabbit as an unconjugated polyclonal reagent, this Antibodies.com antibody recognizes MKK7 (also called MAP2K7), a dual-specificity MAP kinase kinase that functions as a selective upstream activator of the JNK (c-Jun N-terminal kinase) pathway. The target operates inside stress-activated phosphorylation cascades triggered by inflammatory cytokines, UV exposure, and osmotic or genotoxic insults, and it has been linked in published studies to T cell differentiation, neuronal apoptosis, and several cancer-related signaling contexts.

Each vial contains 100 µl of antibody at 1 mg/ml, formulated in PBS with 0.1% sodium azide and 50% glycerol as a cryoprotectant for storage stability at refrigerated conditions. The reagent has been validated for western blot, immunohistochemistry, immunocytochemistry, immunofluorescence, and immunoprecipitation workflows, with confirmed reactivity toward human, mouse, and rat MKK7. The unconjugated format lets researchers couple the antibody to their own fluorophores, enzymes, or beads, supporting flexible assay design across cell biology and signal transduction research.